Spazmotek Plus (N-butilbromide hioscinë, paracetamol)

Spazmotek Plus contains N-butylbromide of hyoscine and paracetamol.

Hyoscine N-butylbromide has anti-muscarinic effect. It has peripheral and parasympatolytic anticholinergic actions as it has ganglion-blocking effect on the smooth muscles of internal organs, and inhibiting the muscarinic effect of acetylcholine. Due to these basic characteristics, it has a spasmolytic effect on the smooth muscles of the gallbladder tract, organs of the urogenital system and gastrointestinal tract.
The analgesic effect of paracetamol adds to the analgesic effect that results from the antispasmodic effect, combining antispasmodic and analgesic effects.
This effective combination is valuable in treating paroxysmal smooth muscle pain.

Indications:
-Gastroenterology: gastrointestinal spasms, stomach or duodenal ulcers, colon spasms, irritated bowel and colitis.
-Hepatology: pain of spasms of the gallbladder and gallstones.
-Urology: ureter sphincter spasms, urolithiasis, spasms during cystoscopy, cysto-ureteroscopy and pyelography.
-Gynecology: dysmenorrhea, uterine spasms and tissue spasms

Contraindications:
-This medicine is contraindicated in patients who are allergic to the active ingredients or other substances present in the formulation.
-It should not be used in patients suffering from glaucoma, urinary retention due to prostate hypertrophy, mechanical stenoses of the gastrointestinal tract, megacolon, myasthenia gravis and tachycardia.

Side effects:
-Allergic reactions in the form of exanthema or thrombocytopenia or allergic leukopenia are very rarely observed.
-Bronchospasm can occur in analgesia induced by analgesics.
-There is a risk for hepato-toxicity due to the effect of paracetamol when Spazmotek Plus is administered in high doses.

Pregnancy and breastfeeding
Pregnancy: Category B.
There are no clinical data regarding safety for use during pregnancy. In case of absolute indication the risk-benefit ratio should be evaluated.
There is insufficient data available on the safety of anticholinergic drugs during breastfeeding. Therefore, they are not recommended for use.
On the other hand, paracetamol excreted in breast milk has no adverse therapeutic effect at therapeutic doses.

This is an OTC medicine, so it can be taken without a doctor’s recommendation.
Before using this medicine carefully read the package leaflet as it contains more detailed information.
Consult your doctor or pharmacist for any doubt.Spazmotek Plus (N-butilbromide hioscinë, paracetamol)