Analgine 500 mg (metamizole sodium)

Analgin contains metamizole sodium, with analgesic and antipyretic properties and weak anti-inflammatory effect.
Analgin also has a spasmolytic effect on the smooth muscles of the uterus, gallbladder and urinary tract.
Inhibits prostaglandin synthesis by inhibiting cyclooxygenase.
The central analgesic action is due to the inhibition of adenylate cyclase activity.
It is indicated in severe or resistant conditions with pain or fever.
Sodium metamizole is rapidly and completely absorbed after oral use.
Maximum plasma concentration is reached after one hour.
Partially bound to plasma proteins.
This medicine is metabolized in the liver.
Do not take Analgin if:
-you are allergic to sodium metamizole, other pyrazolone or pyrazolidine derivatives, to any of the other ingredients present in the formulation.
-you have had agranulocytosis, associated with the use of pyrazolones;
-you have impaired spinal cord function (eg after cytostatic therapy) or pathology of the hematopoietic system, such as granulocytopenia;
– you have had bronchospasm or other anaphylactic reactions (eg urticaria, rhinitis, angioedema) from non-opioid analgesics (eg salicylates, paracetamol, diclofenac, ibuprofen, indomethacin, naproxen);
-you suffer from any metabolic disease (insufficiency of glucose -6-phosphate dehydrogenase, hepatic porphyria);
-you are pregnant;
-the patient is a child younger than 3 years old.
-It should not be administered as an injection to patients with hypotension or circulatory instability.
-together with chlorpromazine because it causes hypothermia and renal failure.
If you think you may have any of the above conditions, do not take this drug.
Consult your doctor first and follow the advice given.
PregnancyCategory B.
Its use is not recommended during the first and third trimester of pregnancy, while in the second trimester it can be administered only if the potential benefit outweighs the potential risk.
BreastfeedingAnalgin metabolites are excreted in breast milk, so this medicine should not be used during breastfeeding.
If you are taking Analgine, it should be at least 48 hours before you breastfeed your baby.
This is an OTC medicine, so it can be taken without a doctor’s recommendation.
Before using this medicine carefully read the package leaflet as it contains more detailed information.
Consult your doctor or pharmacist for any doubt.